Хлордекон: Қауіпті ластағыш және денсаулыққа зияны

the pesticide
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| ImageFile = Chlordecone. png
| ImageSize = 120px
| ImageFile2 = Chlordecone Kepone 3D. png
| ImageSize2 = 120px
| IUPACName = decachloropentacyclo[5.3.0.02.6.03.9.04.8]decan 5 one
| OtherNames = ChlordeconeClordeconeMerex
CAS name: 1,1a,3,3a,4,5,5,5a,5b,6 decachlorooctahydro 1,3,4 metheno 2H cyclobuta[cd]pentalen 2 one
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|Section7=Chembox Hazards
| MainHazards = carcinogen
| IDLH = N. D. Chlordecone is a known persistent organic pollutant (POP) that was banned globally by the Stockholm Convention on Persistent Organic Pollutants in 2009.

Chlordecone is made by dimerizing hexachlorocyclopentadiene and hydrolyzing to a ketone. It is also the main degradation product of mirex. At least 29 people in the area were hospitalized as a result of their exposure to Kepone. Chlordecone is cited amongst a handful of other noxious substances as the driver for Gerald Ford's half hearted approval in 1976 of the Toxic Substances Control Act, which "remains one of the most controversial regulatory bills ever passed". In 2009, chlordecone was included in the Stockholm Convention on Persistent Organic Pollutants, which bans its production and use worldwide. The LC50 (LC = lethal concentration) is 35 μg/ L for Etroplus maculatus, 22–95 μg/kg for blue gill and trout. Chlordecone bioaccumulates in animals by factors up to a million fold. Workers with repeated exposure suffer severe convulsions resulting from degradation of the synaptic junctions. and "significant excesses of deaths were observed for stomach cancer in women and pancreatic cancer in women". Chlordecone has been found to act as an agonist of the GPER (GPR30), which interacts strongly with the estrogen sex hormone estradiol.

The history of chlordecone incidents are reviewed in Who's Poisoning America? : Corporate Polluters and Their Victims in the Chemical Age (1982).

In July 1975, Virginia Governor Mills Godwin Jr. shut down the James River to fishing for 100 miles, from Richmond to the Chesapeake Bay. Due to the pollution risks, many fishermen, marinas, seafood businesses, and restaurants, along with their employees along the river suffered economic losses. In 1981, a large group of these entities sued Allied Chemical in federal district court (Eastern District of Virginia), claiming special economic damages from Allied's negligent damage to the fish and wildlife. In a case that sometimes appears in law school courses on Remedies, the court rejected the traditional "economic loss rule", which requires physical impact causing personal injury or property damage to receive economic damages, and instead allowed a limited group of the plaintiffs—the fishing boat owners, the marinas, and the bait and tackle shops—to recover economic damages from Allied Chemical.

The French islands of Martinique and Guadeloupe are heavily contaminated with chlordecone, following years of its massive and unrestricted use on banana plantations. Despite a 1990 ban on the substance in mainland France, the economically powerful banana planters lobbied intensively to obtain a waiver to keep using Kepone until 1993. They argued that no alternative pesticide was available, which has since been disputed. After the 1993 ban, the banana planters were discreetly granted derogations to use their remaining stocks, and a 2005 report prepared by the French National Assembly states that after the 1993 ban was imposed, the chemical was illegally imported to the islands under the name Curlone, and continued to be used for many years. Since 2003, local authorities in the two islands have restricted the cultivation of various food crops because the soil is badly contaminated by chlordecone. A 2018 large scale study by the French public health agency, Santé publique France, shows that 95% of the inhabitants of Guadeloupe and 92% of those of Martinique are contaminated by the chemical. Guadeloupe has one of the highest prostate cancer diagnosis rates in the world.

Kepone was the name of an American indie rock band from Richmond, Virginia formed in 1991. The Dead Kennedys recorded a song named "Kepone Factory", a satire of the controversy surrounding Allied Signal and their negligence regarding employee safety, for their 1981 album In God We Trust, Inc