2006 жылғы NCAA әйелдер баскетбол турнирінің жеңімпаздары

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The 2006 NCAA Division I women's basketball tournament was held from March 18 to April 4, 2006, at several sites, with the championship game held in Boston. The Maryland Terrapins, coached by Brenda Frese, won their first National Championship, beating the Duke Blue Devils, coached by Gail Goestenkors, 78–75 in overtime. Laura Harper of the Terrapins was named Most Outstanding Player. The field is set at 64 teams, with 31 automatic bids and 33 at large bids. Unlike the men's game, there is no play in game. In addition, the first two rounds and regionals are usually played on "neutral" sites. As of the 2023 tournament, this is the last Final Four where all four teams were coached by women. Until the 2023 tournament, this was the last Women's final four not to include either Connecticut or Tennessee.

In the Albuquerque Regional, Boston College upset the number one seed, Ohio State, in the second round. BC went on to play fifth seeded Utah in the regional semifinal, but Utah won by three points. Utah then played Maryland in the Regional final. With under eight seconds to go in regulation, Utah was trailing by a single point, with Shona Thorburn at the free throw line for two shots. She only made one, and the game went into overtime. This was familiar territory for the Terrapins, who were now playing in the fifth overtime game of their season. They had won the previous four, and would outscore Utah 12–2 to advance to the Final Four. Ultimately though, the top four seeds advance to the regional semifinals, the top two to the final, and top seed North Carolina beat Tennessee to advance to the Final Four. It was their first trip to the Final Four for the Tarheels since 1994, when they had won the National Championship. The San Antonio Regional also largely followed the seeding, although third seeded Stanford upset Oklahoma to reach the regional final. Although top seeded LSU was down by five points at halftime, they came back to beat Stanford by three points to earn a trip to the Final Four. LSU had only a one point lead, when Candice Wiggins drove to the basket but Seimone Augustus stood in the way and took a charge. Wiggins had passed the ball to Krista Rappahahn who hit a three pointer, but it was waved off because of the charge.

Sixty four teams were selected to participate in the 2006 NCAA Tournament. Thirty one conferences were eligible for an automatic bid to the 2006 NCAA tournament.