Стивен Оппенгеймер: генетика, миграции и происхождение человека.

British geneticist

Stephen Oppenheimer (born 1947) is a British paediatrician, geneticist, and writer. He is a graduate of Balliol College, Oxford and an honorary fellow of the Liverpool School of Tropical Medicine. In addition to his work in medicine and tropical diseases, he has published popular works in the fields of genetics and human prehistory. This latter work has been the subject of a number of television and film projects.

Oppenheimer trained in medicine at Oxford and London universities, qualifying in 1971. From 1972 he worked as a clinical paediatrician, mainly in Malaysia, Nepal and Papua New Guinea. He carried out and published clinical research in the areas of nutrition, infectious disease (including malaria), and genetics, focussing on the interactions between nutrition, genetics and infection, in particular iron nutrition, thalassaemia and malaria. From 1979 he moved into medical research and teaching, with positions at the Liverpool School of Tropical Medicine, Oxford University, a research centre in Kilifi, Kenya, and the Universiti Sains Malaysia in Penang. He spent three years undertaking fieldwork in Papua New Guinea, studying the effects of iron supplementation on susceptibility to infection. His fieldwork, published in the late 1980s, identified the role of genetic mutation in malarious areas as a result of natural selection due to its protective effect against malaria, and that different genotypes for alpha thalassaemia traced different migrations out to the Pacific. Following that work, he concentrated on researching the use of unique genetic mutations as markers of ancient migrations.

In 2002, Oppenheimer worked as consultant on a television documentary series, The Real Eve, produced by the American cable TV network the Discovery Channel and directed by Andrew Piddington. The series was known as Where We Came From in the United Kingdom. The "Eve" in the title refers to Mitochondrial Eve, a name used for the most recent common ancestor of all humans in the matrilineal (mother to daughter) line of descent. Following the series, Oppenheimer published a book on the same theme, originally titled Out of Eden in the UK and republished as The Real Eve in the US. This work, published in 2004, focuses on Oppenheimer's hypothesis: that approximately 85 thousand years ago, a group of modern humans migrated from East Africa across the Red Sea to South Asia in a single major exodus numbering no more than a few hundred individuals. This lone group of wanderers, he suggests, were the ancestors of all the peoples of the earth except sub Saharan Africans, their descendants having since migrated all over the Eurasian continent, North Africa, the Pacific islands, and the New World, and radiated into a plurality of physical characteristics, languages, ethnicities and cultures as seen today.

In his 2006 book The Origins of the British (revised in 2007), Oppenheimer argued that neither Anglo Saxons nor Celts had much impact on the genetics of the inhabitants of the British Isles, and that British ancestry mainly traces back to the Palaeolithic Iberian people, now represented best by Basques, instead. He also argued that the Scandinavian input has been underestimated. He published an introduction to his book in Prospect magazine and answered some of his critics in a further Prospect magazine article in June 2007. Recent archaeogenetics studies have contradicted Oppenheimer's theory,
indicating a population replacement in Britain by a migration of Early European Farmers, ultimately from the Aegean, after c. 4,000 BCE, and another population replacement around the middle of the third millennium BCE, when a migration of Bell Beaker groups carrying significant levels of Steppe Ancestry resulted in the replacement of around 90% of the gene pool in Britain.