Ферменттердің толық ақпараттық жүйесі BRENDA

Online database of enzymes

BRENDA (The Comprehensive Enzyme Information System) is an information system representing one of the most comprehensive enzyme repositories. It is an electronic resource that comprises molecular and biochemical information on enzymes that have been classified by the IUBMB. Every classified enzyme is characterized with respect to its catalyzed biochemical reaction. Kinetic properties of the corresponding reactants (that is, substrates and products) are described in detail. BRENDA contains enzyme specific data manually extracted from primary scientific literature and additional data derived from automatic information retrieval methods such as text mining. It provides a web based user interface that allows a convenient and sophisticated access to the data.

BRENDA was founded in 1987 at the former German Research Centre for Biotechnology (now the Helmholtz Centre for Infection Research) in Braunschweig and was originally published as a series of books. Its name was originally an acronym for the BRaunschweig ENzyme DAtabase. From 1996 to 2007, BRENDA was located at the University of Cologne. There, BRENDA developed into a publicly accessible enzyme information system. In 2007, BRENDA returned to Braunschweig. Currently, BRENDA is maintained and further developed at the BRICS ( Braunschweig Integrated Centre of Systems Biology) at the TU Braunschweig. In 2018 BRENDA was appointed to ELIXIR Core Data Resource with fundamental importance to biological and biomedical research and long term preservation of biological data.

A major update of the data in BRENDA is performed twice a year. Besides the upgrade of its content, improvements of the user interface are also incorporated into the BRENDA database.

The use of BRENDA is free of charge. BRENDA is subject to the terms of the Creative Commons license (CC BY 4.0).