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One of the historic seven gates of the London Wall around the City of London

Newgate was one of the historic seven gates of the London Wall around the City of London and one of the six which date back to Roman times. Newgate lay on the west side of the wall and the road issuing from it headed over the River Fleet to Middlesex and western England. Beginning in the 12th century, parts of the gate buildings were used as a gaol, which later developed into Newgate Prison.

It was once thought that Newgate was "New" since it was built after the Roman period but archaeological evidence has shown that it was of Roman origin; it is therefore possible that the gate was so named when the Ludgate became less used due to the building of the fourth St Paul's Cathedral in the early medieval period. It was previously known as Chamberlains Gate, there was a landholding referred to as the Chamberlain's Soke lying just outside Newgate, forming part of the ward of Farringdon Without.

Excavations in 1875, 1903 and 1909 revealed the Roman structure and showed that it consisted of a double roadway between two square flanking guardroom towers. From the 12th century, at least, the gate was used as a prison for debtors and felons. Jack Cade was beheaded publicly in Newgate after the conclusion of his failed rebellion. The notorious Newgate Prison, was later extended to the south on the site of the modern Central Criminal Court on Old Bailey. The gate was demolished in 1767. To the north of the street are the public gardens around the ruins of Christ Church Greyfriars (bombed during World War II) on the site of a medieval Franciscan monastery. To the south is Paternoster Square leading towards St Paul's Cathedral.