Тыныс шығару процесі

Flow of the respiratory current out of an organism
the Ted Chiang short story

Exhalation (or expiration) is the flow of the breath out of an organism. In animals, it is the movement of air from the lungs out of the airways, to the external environment during breathing. This happens due to elastic properties of the lungs, as well as the internal intercostal muscles which lower the rib cage and decrease thoracic volume. As the thoracic diaphragm relaxes during exhalation it causes the tissue it has depressed to rise superiorly and put pressure on the lungs to expel the air. During forced exhalation, as when blowing out a candle, expiratory muscles including the abdominal muscles and internal intercostal muscles generate abdominal and thoracic pressure, which forces air out of the lungs. Exhaled air is 4% carbon dioxide, a waste product of cellular respiration during the production of energy, which is stored as ATP. Exhalation has a complementary relationship to inhalation which together make up the respiratory cycle of a breath.

The main reason for exhalation is to rid the body of carbon dioxide, which is the waste product of gas exchange in humans. Air is brought into the lungs through inhalation. Diffusion in the alveoli allows for the exchange of O2 into the pulmonary capillaries and the removal of CO2 and other gases from the pulmonary capillaries to be exhaled. In order for the lungs to expel air the diaphragm relaxes, which pushes up on the lungs. The air then flows through the trachea then through the larynx and pharynx to the nasal cavity and oral cavity where it is expelled out of the body. Exhalation takes longer than inhalation and it is believed to facilitate better exchange of gases. Parts of the nervous system help to regulate respiration in humans. The exhaled air is not just carbon dioxide; it contains a mixture of other gases. Human breath contains volatile organic compounds (VOCs). These compounds consist of methanol, isoprene, acetone, ethanol and other alcohols. The exhaled mixture also contains ketones, water and other hydrocarbons. It is during exhalation that the olfaction contribution to flavor occurs in contrast to that of ordinary smell which occurs during the inhalation phase.

Spirometry is the measure of lung function. The total lung capacity (TLC), functional residual capacity (FRC), residual volume (RV), and vital capacity (VC) are all values that can be tested using this method. Spirometry is used to help detect, but not diagnose, respiratory issues like COPD, and asthma. It is a simple and cost effective screening method. Further evaluation of a person's respiratory function can be done by assessing the minute ventilation, forced vital capacity (FVC), and forced expiratory volume (FEV). These values differ in men and women because men tend to be larger than women. TLC is the maximum amount of air in the lungs after maximum inhalation. In men the average TLC is 6000 ml, and in women it is 4200 ml. FRC is the amount of air left in the lungs after normal exhalation. Men leave about 2400 ml on average while women retain around 1800 ml. RV is the amount of air left in the lungs after a forced exhalation. The average RV in men is 1200 ml and women 1100 ml. VC is the maximum amount of air that can be exhaled after a maximum inhalation. Men tend to average 4800 ml and women 3100 ml. Smokers, and those with Asthma and COPD, have reduced airflow ability. People with asthma and COPD show decreases in exhaled air due to inflammation of the airways. This inflammation causes narrowing of the airways which allows less air to be exhaled. Numerous things cause inflammation; some examples are cigarette smoke and environmental interactions such as allergies, weather, and exercise. In smokers the inability to exhale fully is due to the loss of elasticity in the lungs. Smoke in the lungs causes them to harden and become less elastic, which prevents the lungs from expanding or shrinking as they normally would. Dead space can be determined by two types of factors which are anatomical and physiological. Some physiological factors are having non perfuse but ventilated alveoli, such as a pulmonary embolism or smoking, excessive ventilation of the alveoli, brought on in relation to perfusion, in people with chronic obstructive lung disease, and "shunt dead space," which is a mistake between the left to right lung that moves the higher concentrations in the venous blood into the arterial side. The anatomical factors are the size of the airway, the valves, and tubing of the respiratory system. Both lungs together have the same amount of surface area as half of a tennis court. Disease such as, emphysema, tuberculosis, can reduce the amount of surface area and elasticity of the lungs. Another big factor in the elasticity of the lungs is smoking because of the residue left behind in the lungs from the smoking. The elasticity of the lungs can be trained to expand further.

Brain control of exhalation can be broken down into voluntary control and involuntary control. During voluntary exhalation, air is held in the lungs and released at a fixed rate. Examples of voluntary expiration include: singing, speaking, exercising, playing an instrument, and voluntary hyperpnea. Involuntary breathing includes metabolic and behavioral breathing.

The neurological pathway of voluntary exhalation is complex and not fully understood. However, a few basics are known. The motor cortex within the cerebral cortex of the brain is known to control voluntary respiration because the motor cortex controls voluntary muscle movement. This is referred to as the corticospinal pathway or ascending respiratory pathway. The pathway of the electrical signal starts in the motor cortex, goes to the spinal cord, and then to the respiratory muscles. The spinal neurons connect directly to the respiratory muscles. Initiation of voluntary contraction and relaxation of the internal and external internal costals has been shown to take place in the superior portion of the primary motor cortex. Using airflow from the lungs, one can control the duration, amplitude, and pitch. While the air is expelled it flows through the glottis causing vibrations, which produces sound. Depending on the glottis movement the pitch of the voice changes and the intensity of the air through the glottis change the volume of the sound produced by the glottis.

Involuntary respiration is controlled by respiratory centers within the medulla oblongata and pons. The medullary respiratory center can be subdivided into anterior and posterior portions. They are called the ventral and dorsal respiratory groups respectively. The pontine respiratory group consists of two parts: the pneumotaxic center and the apneustic center. Autonomic Inspiration is controlled by the pontine respiratory center and both medullary respiratory centers. In our case, the VRG controls autonomic exhalation. Signals from the VRG are sent along the spinal cord to several nerves. These nerves include the intercostals, phrenic, and abdominals. The reason why we yawn is unknown. A common belief is that yawns are a way to regulate the body's levels of O2 and CO2, but studies done in a controlled environment with different levels of O2 and CO2 have disproved that hypothesis. Although there is not a concrete explanation as to why we yawn, others think people exhale as a cooling mechanism for our brains. Studies on animals have supported this idea and it is possible humans could be linked to it as well. What is known is that yawning does ventilate all the alveoli in the lungs.

Several receptor groups in the body regulate metabolic breathing. These receptors signal the respiratory center to initiate inhalation or exhalation. Peripheral chemoreceptors are located in the aorta and carotid arteries. They respond to changing blood levels of oxygen, carbon dioxide, and H+ by signaling the pons and medulla. They tell their students that the "nose is for breathing, the mouth is for eating."