Type I and type II errors

Concepts from statistical hypothesis testing
erroneous outcomes of statistical tests

In statistical hypothesis testing, a type I error, or a false positive, is the rejection of the null hypothesis when it is actually true. For example, an innocent person may be convicted. A type II error, or a false negative, is the failure to reject a null hypothesis that is actually false. For example: a guilty person may be not convicted. Much of statistical theory revolves around the minimization of one or both of these errors, though the complete elimination of either is a statistical impossibility if the outcome is not determined by a known, observable causal process. By selecting a low threshold (cut off) value and modifying the alpha (α) level, the quality of the hypothesis test can be increased. The knowledge of type I errors and type II errors is widely used in medical science, biometrics and computer science. Intuitively, type I errors can be thought of as errors of commission (i. e., the researcher unluckily concludes that something is the fact). For instance, consider a study where researchers compare a drug with a placebo. If the patients who are given the drug get better than the patients given the placebo by chance, it may appear that the drug is effective, but in fact the conclusion is incorrect. By contrast, type II errors are errors of omission. In the example above, if the patients who got the drug did not get better at a higher rate than the ones who got the placebo, but this was a random fluke, that would be a type II error. The consequence of a type II error depends on the size and direction of the missed determination and the circumstances. An expensive cure for one in a million patients may be inconsequential even if it truly is a cure.

In statistical test theory, the notion of a statistical error is an integral part of hypothesis testing. The test goes about choosing about two competing propositions called null hypothesis, denoted by H0 and alternative hypothesis, denoted by H1. This is conceptually similar to the judgement in a court trial. The null hypothesis corresponds to the position of the defendant: just as he is presumed to be innocent until proven guilty, so is the null hypothesis presumed to be true until the data provide convincing evidence against it. The alternative hypothesis corresponds to the position against the defendant. Specifically, the null hypothesis also involves the absence of a difference or the absence of an association. Thus, the null hypothesis can never be that there is a difference or an association. If the result of the test corresponds with reality, then a correct decision has been made. However, if the result of the test does not correspond with reality, then an error has occurred. There are two situations in which the decision is wrong. The null hypothesis may be true, whereas we reject H0. On the other hand, the alternative hypothesis H1 may be true, whereas we do not reject H0. Two types of error are distinguished: type I error and type II error.

The first kind of error is the mistaken rejection of a null hypothesis as the result of a test procedure. This kind of error is called a type I error (false positive) and is sometimes called an error of the first kind. In terms of the courtroom example, a type I error corresponds to convicting an innocent defendant.

A perfect test would have zero false positives and zero false negatives. However, statistical methods are probabilistic, and it cannot be known for certain whether statistical conclusions are correct. Whenever there is uncertainty, there is the possibility of making an error. Considering this nature of statistics science, all statistical hypothesis tests have a probability of making type I and type II errors. The type I error rate is the probability of rejecting the null hypothesis given that it is true. The test is designed to keep the type I error rate below a prespecified bound called the significance level, usually denoted by the Greek letter α (alpha) and is also called the alpha level. Usually, the significance level is set to 0.05 (5%), implying that it is acceptable to have a 5% probability of incorrectly rejecting the true null hypothesis. The rate of the type II error is denoted by the Greek letter β (beta) and related to the power of a test, which equals 1−β. These two types of error rates are traded off against each other: for any given sample set, the effort to reduce one type of error generally results in increasing the other type of error.

The same idea can be expressed in terms of the rate of correct results and therefore used to minimize error rates and improve the quality of hypothesis test. To reduce the probability of committing a type I error, making the alpha value more stringent is quite simple and efficient. To decrease the probability of committing a type II error, which is closely associated with analyses' power, either increasing the test's sample size or relaxing the alpha level could increase the analyses' power. A test statistic is robust if the type I error rate is controlled. Varying different threshold (cut off) value could also be used to make the test either more specific or more sensitive, which in turn elevates the test quality. For example, imagine a medical test, in which an experimenter might measure the concentration of a certain protein in the blood sample. The experimenter could adjust the threshold (black vertical line in the figure) and people would be diagnosed as having diseases if any number is detected above this certain threshold. According to the image, changing the threshold would result in changes in false positives and false negatives, corresponding to movement on the curve.

Since in a real experiment it is impossible to avoid all type I and type II errors, it is important to consider the amount of risk one is willing to take to falsely reject H0 or accept H0. The solution to this question would be to report the p value or significance level α of the statistic. For example, if the p value of a test statistic result is estimated at 0.0596, then there is a probability of 5.96% that we falsely reject H0. Or, if we say, the statistic is performed at level α, like 0.05, then we allow to falsely reject H0 at 5%. A significance level α of 0.05 is relatively common, but there is no general rule that fits all scenarios.

The speed limit of a freeway in the United States is 120 kilometers per hour (75 mph). A device is set to measure the speed of passing vehicles. Suppose that the device will conduct three measurements of the speed of a passing vehicle, recording as a random sample X1, X2, X3. The traffic police will or will not fine the drivers depending on the average speed That is to say, the test statistic

In addition, we suppose that the measurements X1, X2, X3 are modeled as normal distribution N(μ,2). Then, T should follow N(μ,2/) and the parameter μ represents the true speed of passing vehicle. In this experiment, the null hypothesis H0 and the alternative hypothesis H1 should be

H0: μ=120 against H1: μ>120. If we perform the statistic level at α=0.05, then a critical value c should be calculated to solve

According to change of units rule for the normal distribution. Referring to Z table, we can get

Here, the critical region. That is to say, if the recorded speed of a vehicle is greater than critical value 121.9, the driver will be fined. However, there are still 5% of the drivers are falsely fined since the recorded average speed is greater than 121.9 but the true speed does not pass 120, which we say, a type I error. The type II error corresponds to the case that the true speed of a vehicle is over 120 kilometers per hour but the driver is not fined. For example, if the true speed of a vehicle μ=125, the probability that the driver is not fined can be calculated as

which means, if the true speed of a vehicle is 125, the driver has the probability of 0.36% to avoid the fine when the statistic is performed at level α=0.05, since the recorded average speed is lower than 121.9. If the true speed is closer to 121.9 than 125, then the probability of avoiding the fine will also be higher. The tradeoffs between type I error and type II error should also be considered. That is, in this case, if the traffic police do not want to falsely fine innocent drivers, the level α can be set to a smaller value, like 0.01. However, if that is the case, more drivers whose true speed is over 120 kilometers per hour, like 125, would be more likely to avoid the fine.

It is standard practice for statisticians to conduct tests in order to determine whether or not a "speculative hypothesis" concerning the observed phenomena of the world (or its inhabitants) can be supported. The results of such testing determine whether a particular set of results agrees reasonably (or does not agree) with the speculated hypothesis. On the basis that it is always assumed, by statistical convention, that the speculated hypothesis is wrong, and the so called "null hypothesis" that the observed phenomena simply occur by chance (and that, as a consequence, the speculated agent has no effect) – the test will determine whether this hypothesis is right or wrong. This is why the hypothesis under test is often called the null hypothesis (most likely, coined by Fisher (1935, p. 19)), because it is this hypothesis that is to be either nullified or not nullified by the test. When the null hypothesis is nullified, it is possible to conclude that data support the "alternative hypothesis" (which is the original speculated one). The consistent application by statisticians of Neyman and Pearson's convention of representing "the hypothesis to be tested" (or "the hypothesis to be nullified") with the expression H0 has led to circumstances where many understand the term "the null hypothesis" as meaning "the nil hypothesis" – a statement that the results in question have arisen through chance. This is not necessarily the case – the key restriction, as per Fisher (1966), is that "the null hypothesis must be exact, that is free from vagueness and ambiguity, because it must supply the basis of the 'problem of distribution', of which the test of significance is the solution." As a consequence of this, in experimental science the null hypothesis is generally a statement that a particular treatment has no effect; in observational science, it is that there is no difference between the value of a particular measured variable, and that of an experimental prediction.

In the practice of medicine, the differences between the applications of screening and testing are considerable.

Screening involves relatively cheap tests that are given to large populations, none of whom manifest any clinical indication of disease (e. g., Pap smears). Testing involves far more expensive, often invasive, procedures that are given only to those who manifest some clinical indication of disease, and are most often applied to confirm a suspected diagnosis. For example, most states in the US require newborns to be screened for phenylketonuria and hypothyroidism, among other congenital disorders. Hypothesis: "The newborns have phenylketonuria and hypothyroidism". Null hypothesis (H0): "The newborns do not have phenylketonuria and hypothyroidism". Type I error (false positive): The true fact is that the newborns do not have phenylketonuria and hypothyroidism but we consider they have the disorders according to the data. Type II error (false negative): The true fact is that the newborns have phenylketonuria and hypothyroidism but we consider they do not have the disorders according to the data. Although they display a high rate of false positives, the screening tests are considered valuable because they greatly increase the likelihood of detecting these disorders at a far earlier stage. The simple blood tests used to screen possible blood donors for HIV and hepatitis have a significant rate of false positives; however, physicians use much more expensive and far more precise tests to determine whether a person is actually infected with either of these viruses. Perhaps the most widely discussed false positives in medical screening come from the breast cancer screening procedure mammography. The US rate of false positive mammograms is up to 15%, the highest in world. One consequence of the high false positive rate in the US is that, in any 10 year period, half of the American women screened receive a false positive mammogram. False positive mammograms are costly, with over $100 million spent annually in the U. S. on follow up testing and treatment. They also cause women unneeded anxiety. As a result of the high false positive rate in the US, as many as 90–95% of women who get a positive mammogram do not have the condition. The lowest rate in the world is in the Netherlands, 1%. The lowest rates are generally in Northern Europe where mammography films are read twice and a high threshold for additional testing is set (the high threshold decreases the power of the test). The ideal population screening test would be cheap, easy to administer, and produce zero false negatives, if possible. Such tests usually produce more false positives, which can subsequently be sorted out by more sophisticated (and expensive) testing.

False negatives and false positives are significant issues in medical testing. Hypothesis: "The patients have the specific disease". Null hypothesis (H0): "The patients do not have the specific disease". Type I error (false positive): The true fact is that the patients do not have a specific disease but the physician judges the patient is ill according to the test reports. Type II error (false negative): The true fact is that the disease is actually present but the test reports provide a falsely reassuring message to patients and physicians that the disease is absent. False positives can also produce serious and counter intuitive problems when the condition being searched for is rare, as in screening. If a test has a false positive rate of one in ten thousand, but only one in a million samples (or people) is a true positive, most of the positives detected by that test will be false. The probability that an observed positive result is a false positive may be calculated using Bayes' theorem. False negatives produce serious and counter intuitive problems, especially when the condition being searched for is common. If a test with a false negative rate of only 10% is used to test a population with a true occurrence rate of 70%, many of the negatives detected by the test will be false. This sometimes leads to inappropriate or inadequate treatment of both the patient and their disease. A common example is relying on cardiac stress tests to detect coronary atherosclerosis, even though cardiac stress tests are known to only detect limitations of coronary artery blood flow due to advanced stenosis.

Biometric matching, such as for fingerprint recognition, facial recognition or iris recognition, is susceptible to type I and type II errors. Hypothesis: "The input does not identify someone in the searched list of people". Null hypothesis: "The input does identify someone in the searched list of people". Type I error (false reject rate): The true fact is that the person is someone in the searched list but the system concludes that the person is not according to the data. Type II error (false match rate): The true fact is that the person is not someone in the searched list but the system concludes that the person is someone whom we are looking for according to the data. The probability of type I errors is called the "false reject rate" (FRR) or false non match rate (FNMR), while the probability of type II errors is called the "false accept rate" (FAR) or false match rate (FMR). If the system is designed to rarely match suspects then the probability of type II errors can be called the "false alarm rate". On the other hand, if the system is used for validation (and acceptance is the norm) then the FAR is a measure of system security, while the FRR measures user inconvenience level.

False positives are routinely found every day in airport security screening, which are ultimately visual inspection systems. The installed security alarms are intended to prevent weapons being brought onto aircraft; yet they are often set to such high sensitivity that they alarm many times a day for minor items, such as keys, belt buckles, loose change, mobile phones, and tacks in shoes. Hypothesis: "The item is a weapon". Null hypothesis: "The item is not a weapon". Type I error (false positive): The true fact is that the item is not a weapon but the system still sounds an alarm. Type II error (false negative) The true fact is that the item is a weapon but the system keeps silent at this time. The ratio of false positives (identifying an innocent traveler as a terrorist) to true positives (detecting a would be terrorist) is, therefore, very high; and because almost every alarm is a false positive, the positive predictive value of these screening tests is very low. The relative cost of false results determines the likelihood that test creators allow these events to occur. As the cost of a false negative in this scenario is extremely high (not detecting a bomb being brought onto a plane could result in hundreds of deaths) whilst the cost of a false positive is relatively low (a reasonably simple further inspection) the most appropriate test is one with a low statistical specificity but high statistical sensitivity (one that allows a high rate of false positives in return for minimal false negatives).