5-MeO αMT: Қауіпті галлюциногендік зат және құқықтық мәртебесі

Chemical compound

5 MeO αMT or 5 methoxy α methyltryptamine, α,O Dimethylserotonin (Alpha O) is a potent psychedelic tryptamine. It is soluble in ethanol.

The sympathomimetic effects may in turn be caused by 5 MeO AMT's structural similarity to the amphetamines. As noted by Alexander Shulgin, the alpha methylated tryptamines can be looked at as the tryptamine homologues of the amphetamines (alpha methylated phenethylamines). Mechanisms of action such as inhibition of monoamine reuptake may be involved also.

Binding Sites Binding Affinity Ki (μM) 5 HT1A 0.046 5 HT2A 0.034 5 HT2C 0.09 D1 >25 D2 >25 D3 >25 α1A >12 α2A 11 TAAR1 1.1 H1 >25 SERT 12 DAT >26 NET >22

5 MeO AMT is supposedly sold in 4 mg tablets by the street name Alpha O and taken as a recreational drug. Since the DEA arrests of the makers of a huge percentage of the United States' LSD in 2000, 5 MeO AMT may have occasionally been sold under the guise of LSD in liquid, sugar cube, or blotter form, though this may be due to DEA reports of finding it on sugar cubes and blotters like LSD. The most common route of administration for 5 MeO AMT is orally. Anecdotal reports, however, have described snorting or smoking the substance. Intravenous (IV) and intramuscular (IM) routes are rarely, if ever, used outside research settings due to the high potency, powerful effects and quicker onset.

If misrepresented as LSD, 5 MeO AMT can be extremely dangerous; users may take a number of "hits" of 5 MeO AMT, assuming that it is LSD. Unlike LSD, which is very safe in overdose, 5 MeO AMT can be very harmful or fatal. Particularly sensitive individuals can experience symptoms of overdose at dosages in the normal (for most users) range — as low as 20 mg. This has led to at least a few hospitalizations and possibly more than one death. It is likely that the overdose potential of the compound is due to its sympathomimetic effects, as the side effects noted in overdose cases include cardiac arrhythmia and seizure. It also seems that oral consumption is safer than insufflation. Gloria Discerni, 18, died after overdosing on a drug initially believed to be LSD. Authorities learned months later that the drug wasn't LSD but a "designer drug" identified as 5 MeO AMT.

5 MeO aMT is considered a Schedule 9 prohibited substance in Australia under the Poisons Standard (October 2015). A Schedule 9 substance is a substance which may be abused or misused, the manufacture, possession, sale or use of which should be prohibited by law except when required for medical or scientific research, or for analytical, teaching or training purposes with approval of Commonwealth and/or State or Territory Health Authorities.

5 MeO αMT was made illegal in the United Kingdom as of 7 January 2015, along with 5 MeO DALT. This was following the events of 10 June 2014 when the Advisory Council on the Misuse of Drugs recommended that 5 MeO αMT be scheduled as a class A drug by updating the blanket ban clause on tryptamines.

5 MeO AMT is unscheduled at the federal level in the United States. However, the DEA considers the chemical a controlled substance analogue. The agency’s opinion on this matter may change at any time.

5 MeO AMT is a Schedule I controlled substance in the state of Florida, making it illegal to buy, sell, or possess.