Альдозалар: құрылымы, түрлері және қасиеттері

Class of monosaccharides
An aldose is a monosaccharide (a simple sugar) with a carbon backbone chain with a carbonyl group on the endmost carbon atom, making it an aldehyde, and hydroxyl groups connected to all the other carbon atoms. Aldoses can be distinguished from ketoses, which have the carbonyl group away from the end of the molecule, and are therefore ketones.

Like most carbohydrates, simple aldoses have the general chemical formula Cn(H2O)n. Because formaldehyde (n=1) and glycolaldehyde (n=2) are not generally considered to be carbohydrates, the simplest possible aldose is the triose glyceraldehyde, which only contains three carbon atoms. Because they have at least one asymmetric carbon center, all aldoses exhibit stereoisomerism. Aldoses can exist in either a form or form. The determination is made based on the chirality of the asymmetric carbon furthest from the aldehyde end, namely the second last carbon in the chain. Aldoses with alcohol groups on the right of the Fischer projection are aldoses, and those with alcohols on the left are aldoses. aldoses are more common than aldoses in nature. The test relies on the dehydration reaction which occurs more quickly in ketoses, so that while aldoses react slowly, producing a light pink color, ketoses react more quickly and strongly to produce a dark red color. Aldoses can isomerize to ketoses through the Lobry de Bruyn van Ekenstein transformation.

Aldoses are commonly referred to by names specific to one stereoisomer of the compound. This distinction is especially vital in biochemistry, as many systems can only use one enantiomer of the carbohydrate and not the other. However, aldoses are not locked into any one conformation: they can and do fluctuate between different forms. Aldoses can tautomerize to ketoses in a dynamic process with an enol intermediate (more specifically, an enediol). This process is reversible, so aldoses and ketoses can be thought of as being in equilibrium with each other. However, aldehydes and ketones are almost always more stable than the corresponding enol forms, so the aldo and keto forms normally predominate. This process, with its enol intermediate, also allows stereoisomerization. Basic solutions accelerate the interconversion of isomers. Carbohydrates with more than four carbon atoms exist in an equilibrium between the closed ring, or cyclic form, and the open chain form. Cyclic aldoses are usually drawn as Haworth projections, and open chain forms are commonly drawn as Fischer projections, both of which represent important stereochemical information about the forms they depict.