Стериоидный диабет: причины, диагностика и лечение.

Steroid diabetes or steroid induced diabetes is characterized as an unusual rise in blood sugar that is linked to the use of glucocorticoids in a patient who may or may not have had diabetes mellitus in the past.

Steroid diabetes is caused by the use of glucocorticoids. Glycemic control can be impacted by other immunosuppressive medications through different mechanisms, which could complicate the effects of glucocorticoid therapy. There is an inverse correlation between serum magnesium levels and glycemic control, according to several studies. Although chronic hepatitis C virus (HCV) infection is thought to be a separate risk factor for the development of diabetes in both the general population and liver transplant recipients, liver disease is known to exacerbate impaired glucose tolerance.

The American Diabetes Association defines the following criteria for the diagnosis of diabetes: a HbA1c of 6.5%, an 8 hour fasting blood glucose of 7.0 mmol/L (126 mg/dL), a 2 hour oral glucose tolerance test (OGTT) of ≥ 11.1 mmol/L (200 mg/dL), or in patients exhibiting hyperglycemic symptoms, a random plasma glucose of ≥ 11.1 mmol/L (200 mg/dL).

Like with all forms of diabetes, lifestyle modification, including exercise and dietary counseling to offer options that might lessen post prandial hyperglycemia, is the first step toward improving glycemic control. Current guidelines may not adequately address this because the initiation of glucocorticoids can result in post prandial hyperglycemia and the tapering of glucocorticoids can normalize glycemic control. The most accommodating option for patients is still basal bolus insulin therapy, which consists of three parts: basal insulin, prandial insulin, and supplemental correction factor insulin.