Метохлор: Устаревший инсектицид и его воздействие на здоровье

Synthetic organochloride insecticide, now obsolete. Methoxychlor is a synthetic organochloride insecticide, now obsolete. Tradenames for methoxychlor include Chemform, Maralate, Methoxo, Methoxcide, Metox, and Moxie.

Methoxychlor was used to protect crops, ornamentals, livestock, and pets against fleas, mosquitoes, cockroaches, and other insects. It was intended to be a replacement for DDT, but has since been banned for use as a pesticide based on its acute toxicity, bioaccumulation, and endocrine disruption activity. Its degradation may take many months. Methoxychlor is ingested and absorbed by living organisms, and it accumulates in the food chain. Some metabolites may have unwanted side effects.

The use of methoxychlor as a pesticide was banned in the United States in 2003 and in the European Union in 2002.

Human exposure to methoxychlor occurs via air, soil, and water, primarily in people who work with the substance or who are exposed to air, soil, or water that has been contaminated. It is unknown how quickly and efficiently the substance is absorbed by humans who have been exposed to contaminated air or via skin contact. Such effects adversely affect both the male and female reproductive systems. It is expected that this "could occur in humans" but has not been proven. Little information is available regarding effects on human pregnancy and children, but it is assumed from animals studies that methoxychlor crosses the placenta, and it has been detected in human milk Exposure to children may be different than in adults because they tend to play on the ground, further, their reproductive system may be more sensitive to the effects of methoxychlor as an endocrine disruptor. Food contamination may occur at low levels and it is recommended to wash all foods. A number of hazardous waste sites are known to contain methoxychlor. Maximum pesticide residue limits for the EU/UK are set at 0.01 mg/kg for oranges and 0.01 mg/kg for apples.