Тері түсінің қалыптыдан ақыртуы

Area of skin becoming lighter than the baseline skin color

Hypopigmentation is characterized specifically as an area of skin becoming lighter than the baseline skin color, but not completely devoid of pigment. This is not to be confused with depigmentation, which is characterized as the absence of all pigment. Some common genetic causes include mutations in the tyrosinase gene or OCA2 gene. As melanin pigments tend to be in the skin, eye, and hair, these are the commonly affected areas in those with hypopigmentation.

Areas of lighter pigmentation can be indications of hypopigmentation. Biopsies and genetic information are also used to diagnose.

Often, hypopigmentation can be brought on by laser treatments; however, the hypopigmentation can be treated with other lasers or light sources. Micropigmentation can also be used to obtain a more normal appearance of the hypopigmentated skin. Treatment for hypopigmentation depends on the initial cause of the discoloration. +Treatments for HypopigmentationInitial Cause of DiscolorationTreatmentIdiopathic guttate hypomelanosisNo treatmentPostinflammatory hypopigmentationTreat the underlying inflammatory disease to restore pigmentationPityriasis versicolorA topical ointment, such as selenium sulfide 2.5% or imidazoles. Can also use oral medications, such as oral imidazoles or triazoles. VitiligoTopical steroids, including calcineurin inhibitors. Patients can also have transplants if they are stable or a depigmentation with topical MBEH if the patient has widespread discoloration. Chemical or drug induced leukodermaAvoidance of causative agent with subsequent treatment similar to vitiligo. PiebaldismNone; occasionally transplants.