Стигмастерол: қасиеттері, қолданылуы және денсаулыққа әсері

chembox
| Verifiedfields = changed
| Watchedfields = changed
| verifiedrevid = 450634143
| ImageFile=Stigmasterin. svg
| ImageSize=220px
| ImageFile1 = Stigmasterin molecule ball. png
| ImageSize1 = 250
| ImageAlt1 = Ball and stick model of stigmasterol
| IUPACName = Stigmasta 5,22 dien 3β ol
| SystematicName = (1R,3aS,3bS,7S,9aR,9bS,11aR) 1 [(2R,3E,5S) 5 Ethyl 6 methylhept 3 en 2 yl] 9a,11a dimethyl 2,3,3a,3b,4,6,7,8,9,9a,9b,10,11,11a tetradecahydro 1H cyclopenta[a]phenanthren 7 ol
| OtherNames= Stigmasterin; Wulzen anti stiffness factor
|Section1=
|Section2=Chembox Properties
| C=29
| H=48
| O=1
| Appearance= White solid
| Density=
| BoilingPt=
| MeltingPtC=160 to 164
| MeltingPt ref = In the European Union, it is a food additive listed with E number E499, and may be used in food manufacturing to increase the phytosterol content, potentially lowering the levels of LDL cholesterol.

Once called Wulzen factor in the mid 20th century, stigmasterol was discovered by the University of California physiologist Rosalind Wulzen (born 1886).

Stigmasterol is a food additive in manufactured food products in the United Kingdom and European Union. It was introduced as a precursor by Percy Lavon Julian for industrial large scale manufacture of semisynthetic progesterone, a valuable human hormone that plays an important physiological role in the regulatory and tissue rebuilding mechanisms related to estrogen effects, as well as acting as an intermediate in the biosynthesis of androgens, estrogens, and corticoids. It is also used as the precursor of vitamin D3. The Upjohn company used stigmasterol as the starting raw material for commercial synthesis of cortisone in 1959.

As one of the major phytosterols, stigmasterol is included among sterol compounds in the diet having potential to reduce the risk of cardiovascular diseases.

Being a steroid, stigmasterol is precursor of anabolic steroid boldenone. Boldenone undecylenate is commonly used in veterinary medicine to induce growth in cattle, but it is also one of the most commonly abused anabolic steroids in sports. This led to suspicion that some athletes testing positive for boldenone didn't consume the steroid itself, but rather consumed foods rich in stigmasterol; this turned out not to be the case.