Кіріспе
Мысықтарда споротрихоз кездеседі, сондай-ақ целлюлит дамуы мүмкін. Жұқтырған жануарларды оқшаулау – профилактикалық шаралардың бірі. Жұқтырған мысықтардан адамға инфекция таралу қаупін тиісті биологиялық қауіпсіздік шаралары арқылы, оның ішінде споротрихоз күдікті мысықты қарағанда жеке қорғаныш құралдарын кию және мысықтың соңынан қол, қару және киімді жуу арқылы азайтуға болады. Ауызға қабылданатын калий йодиді.
Potassium iodide is an anti fungal drug that is widely used as a treatment for cutaneous sporotrichosis. Despite its wide use, there is no high quality evidence for or against this practice. Further studies are needed to assess the efficacy and safety of oral potassium iodide in the treatment of sporotrichosis. Itraconazole (Sporanox) and fluconazole
These are antifungal drugs. Itraconazole is currently the drug of choice and is significantly more effective than fluconazole. Fluconazole should be reserved for patients who cannot tolerate itraconazole. Amphotericin B
This antifungal medication is delivered intravenously. Many patients, however, cannot tolerate Amphotericin B due to its potential side effects of fever, nausea, and vomiting. Lipid formulations of amphotericin B are usually recommended instead of amphotericin B deoxycholate because of a better adverse effect profile. Amphotericin B can be used for severe infection during pregnancy. For children with disseminated or severe disease, amphotericin B deoxycholate can be used initially, followed by itraconazole. In case of sporotrichosis meningitis, the patient may be given a combination of Amphotericin B and 5 fluorocytosine/Flucytosine. Terbinafine
500mg and 1000mg daily dosages of terbinafine for twelve to 24 weeks has been used to treat cutaneous sporotrichosis. Newer triazoles
Several studies have shown that posaconazole has in vitro activity similar to that of amphotericin B and itraconazole; therefore, it shows promise as an alternative therapy. However, voriconazole susceptibility varies. Because the correlation between in vitro data and clinical response has not been demonstrated, there is insufficient evidence to recommend either posaconazole or voriconazole for treatment of sporotrichosis at this time.
Калий йодиді – терідегі споротрихозды емдеуде кеңінен қолданылатын құрамында саңырауқұлаққа қарсы әсері бар препарат. Көп қолданылуына қарамастан, осы тәжірибені қолдауға немесе оған қарсы жоғары сапалы деректер жоқ. Споротрихозды емдеуде ауызға қабылданатын калий йодидінің тиімділігі мен қауіпсіздігін бағалау үшін қосымша зерттеулер қажет. Итраконазол (Споранокс) және флуконазол.
Potassium iodide is an anti fungal drug that is widely used as a treatment for cutaneous sporotrichosis. Despite its wide use, there is no high quality evidence for or against this practice. Further studies are needed to assess the efficacy and safety of oral potassium iodide in the treatment of sporotrichosis. Itraconazole (Sporanox) and fluconazole
These are antifungal drugs. Itraconazole is currently the drug of choice and is significantly more effective than fluconazole. Fluconazole should be reserved for patients who cannot tolerate itraconazole. Amphotericin B
This antifungal medication is delivered intravenously. Many patients, however, cannot tolerate Amphotericin B due to its potential side effects of fever, nausea, and vomiting. Lipid formulations of amphotericin B are usually recommended instead of amphotericin B deoxycholate because of a better adverse effect profile. Amphotericin B can be used for severe infection during pregnancy. For children with disseminated or severe disease, amphotericin B deoxycholate can be used initially, followed by itraconazole. In case of sporotrichosis meningitis, the patient may be given a combination of Amphotericin B and 5 fluorocytosine/Flucytosine. Terbinafine
500mg and 1000mg daily dosages of terbinafine for twelve to 24 weeks has been used to treat cutaneous sporotrichosis. Newer triazoles
Several studies have shown that posaconazole has in vitro activity similar to that of amphotericin B and itraconazole; therefore, it shows promise as an alternative therapy. However, voriconazole susceptibility varies. Because the correlation between in vitro data and clinical response has not been demonstrated, there is insufficient evidence to recommend either posaconazole or voriconazole for treatment of sporotrichosis at this time.
Бұл – саңырауқұлаққа қарсы препараттар. Қазіргі таңда итраконазол басымдыққа ие және флуконазолға қарағанда әлдеқайда тиімді. Флуконазол итраконазолға төзбейтін пациенттерге ғана тағайындалуы керек. Амфотерицин B.
Potassium iodide is an anti fungal drug that is widely used as a treatment for cutaneous sporotrichosis. Despite its wide use, there is no high quality evidence for or against this practice. Further studies are needed to assess the efficacy and safety of oral potassium iodide in the treatment of sporotrichosis. Itraconazole (Sporanox) and fluconazole
These are antifungal drugs. Itraconazole is currently the drug of choice and is significantly more effective than fluconazole. Fluconazole should be reserved for patients who cannot tolerate itraconazole. Amphotericin B
This antifungal medication is delivered intravenously. Many patients, however, cannot tolerate Amphotericin B due to its potential side effects of fever, nausea, and vomiting. Lipid formulations of amphotericin B are usually recommended instead of amphotericin B deoxycholate because of a better adverse effect profile. Amphotericin B can be used for severe infection during pregnancy. For children with disseminated or severe disease, amphotericin B deoxycholate can be used initially, followed by itraconazole. In case of sporotrichosis meningitis, the patient may be given a combination of Amphotericin B and 5 fluorocytosine/Flucytosine. Terbinafine
500mg and 1000mg daily dosages of terbinafine for twelve to 24 weeks has been used to treat cutaneous sporotrichosis. Newer triazoles
Several studies have shown that posaconazole has in vitro activity similar to that of amphotericin B and itraconazole; therefore, it shows promise as an alternative therapy. However, voriconazole susceptibility varies. Because the correlation between in vitro data and clinical response has not been demonstrated, there is insufficient evidence to recommend either posaconazole or voriconazole for treatment of sporotrichosis at this time.
Бұл саңырауқұлаққа қарсы препарат тамырға жіберіледі. Алайда, көптеген пациенттер Амфотерицин B-ні қабылдауға шыдамайды, себебі оның ыстық, жүрек ауруы және құсу сияқты жағымсыз әсерлері болуы мүмкін. Амфотерицин B-нің липидтік формалары амфотерицин B дезоксихолатынан гөрі жақсырақ қабылданады, себебі олар жағымсыз әсерлердің азаюын қамтамасыз етеді. Амфотерицин B жүктілік кезінде ауыр инфекция жағдайында қолданылуы мүмкін. Жалпыланған немесе ауыр жағдайы бар балаларға алдымен амфотерицин B дезоксихолаты, содан кейін итраконазол тағайындалуы мүмкін. Споротрихоздық менингит жағдайында пациентке Амфотерицин B және 5-фторцитозин/флуцитозин комбинациясы берілуі мүмкін. Тербинафин.
Potassium iodide is an anti fungal drug that is widely used as a treatment for cutaneous sporotrichosis. Despite its wide use, there is no high quality evidence for or against this practice. Further studies are needed to assess the efficacy and safety of oral potassium iodide in the treatment of sporotrichosis. Itraconazole (Sporanox) and fluconazole
These are antifungal drugs. Itraconazole is currently the drug of choice and is significantly more effective than fluconazole. Fluconazole should be reserved for patients who cannot tolerate itraconazole. Amphotericin B
This antifungal medication is delivered intravenously. Many patients, however, cannot tolerate Amphotericin B due to its potential side effects of fever, nausea, and vomiting. Lipid formulations of amphotericin B are usually recommended instead of amphotericin B deoxycholate because of a better adverse effect profile. Amphotericin B can be used for severe infection during pregnancy. For children with disseminated or severe disease, amphotericin B deoxycholate can be used initially, followed by itraconazole. In case of sporotrichosis meningitis, the patient may be given a combination of Amphotericin B and 5 fluorocytosine/Flucytosine. Terbinafine
500mg and 1000mg daily dosages of terbinafine for twelve to 24 weeks has been used to treat cutaneous sporotrichosis. Newer triazoles
Several studies have shown that posaconazole has in vitro activity similar to that of amphotericin B and itraconazole; therefore, it shows promise as an alternative therapy. However, voriconazole susceptibility varies. Because the correlation between in vitro data and clinical response has not been demonstrated, there is insufficient evidence to recommend either posaconazole or voriconazole for treatment of sporotrichosis at this time.
Тербинафиннің тәулігіне 500 мг және 1000 мг дозалары 12-24 апта бойы терідегі споротрихозды емдеу үшін қолданылған. Жаңа триазолдар.
Potassium iodide is an anti fungal drug that is widely used as a treatment for cutaneous sporotrichosis. Despite its wide use, there is no high quality evidence for or against this practice. Further studies are needed to assess the efficacy and safety of oral potassium iodide in the treatment of sporotrichosis. Itraconazole (Sporanox) and fluconazole
These are antifungal drugs. Itraconazole is currently the drug of choice and is significantly more effective than fluconazole. Fluconazole should be reserved for patients who cannot tolerate itraconazole. Amphotericin B
This antifungal medication is delivered intravenously. Many patients, however, cannot tolerate Amphotericin B due to its potential side effects of fever, nausea, and vomiting. Lipid formulations of amphotericin B are usually recommended instead of amphotericin B deoxycholate because of a better adverse effect profile. Amphotericin B can be used for severe infection during pregnancy. For children with disseminated or severe disease, amphotericin B deoxycholate can be used initially, followed by itraconazole. In case of sporotrichosis meningitis, the patient may be given a combination of Amphotericin B and 5 fluorocytosine/Flucytosine. Terbinafine
500mg and 1000mg daily dosages of terbinafine for twelve to 24 weeks has been used to treat cutaneous sporotrichosis. Newer triazoles
Several studies have shown that posaconazole has in vitro activity similar to that of amphotericin B and itraconazole; therefore, it shows promise as an alternative therapy. However, voriconazole susceptibility varies. Because the correlation between in vitro data and clinical response has not been demonstrated, there is insufficient evidence to recommend either posaconazole or voriconazole for treatment of sporotrichosis at this time.
Бірнеше зерттеулер көрсеткендей, позаконазолдың амфотерицин B және итраконазолға ұқсас in vitro белсенділігі бар, сондықтан ол баламалы ем ретінде үміт береді. Алайда, вориконазолға сезімталдық әртүрлі болуы мүмкін. In vitro деректері мен клиникалық жауап арасындағы байланыс анықталмағандықтан, қазіргі уақытта споротрихозды емдеу үшін позаконазолды немесе вориконазолды ұсынуға жеткілікті дәлелдер жоқ.
Potassium iodide is an anti fungal drug that is widely used as a treatment for cutaneous sporotrichosis. Despite its wide use, there is no high quality evidence for or against this practice. Further studies are needed to assess the efficacy and safety of oral potassium iodide in the treatment of sporotrichosis. Itraconazole (Sporanox) and fluconazole
These are antifungal drugs. Itraconazole is currently the drug of choice and is significantly more effective than fluconazole. Fluconazole should be reserved for patients who cannot tolerate itraconazole. Amphotericin B
This antifungal medication is delivered intravenously. Many patients, however, cannot tolerate Amphotericin B due to its potential side effects of fever, nausea, and vomiting. Lipid formulations of amphotericin B are usually recommended instead of amphotericin B deoxycholate because of a better adverse effect profile. Amphotericin B can be used for severe infection during pregnancy. For children with disseminated or severe disease, amphotericin B deoxycholate can be used initially, followed by itraconazole. In case of sporotrichosis meningitis, the patient may be given a combination of Amphotericin B and 5 fluorocytosine/Flucytosine. Terbinafine
500mg and 1000mg daily dosages of terbinafine for twelve to 24 weeks has been used to treat cutaneous sporotrichosis. Newer triazoles
Several studies have shown that posaconazole has in vitro activity similar to that of amphotericin B and itraconazole; therefore, it shows promise as an alternative therapy. However, voriconazole susceptibility varies. Because the correlation between in vitro data and clinical response has not been demonstrated, there is insufficient evidence to recommend either posaconazole or voriconazole for treatment of sporotrichosis at this time.
Басқа жануарлар
Споротрихоз үй жануарларында және жабайы сүтқоректілерде кездесе алады. Ветеринарияда ең көп көрінетіні мысықтар мен жылқыларда. Мысықтарда тері споротрихозының ерекше ауыр түрі болады. Жұқтырған мысықтарда іріңді бездер, целлюлит немесе антибиотиктермен емдегенде жазылмаған жаралар пайда болуы мүмкін. Споротрихоз адамға жануарлардан жұғады (зооноз). Жұқтырған мысықтардың тері зақымдарынан көп мөлшерде Sporothrix микроорганизмдері бөлінеді, сондықтан оларды ұстаған адамдарға инфекция жұғуы мүмкін. Мысықтар инфекцияның ең көп таралған көзі болғанымен, бұл ауру иттің, егеуқұйрықтың, батпақ тышқанының және армадилланың арасынан да адамға жұққан жағдайлар бар.