Antilocapridae

Family of mammals belonging to even toed ungulates

The Antilocapridae are a family of ruminant artiodactyls endemic to North America. Their closest extant relatives are the giraffids. Only one species, the pronghorn (Antilocapra americana), is living today; all other members of the family are extinct. The living pronghorn is a small ruminant mammal resembling an antelope.

In most respects, antilocaprids resemble other ruminants. They have a complex, four chambered stomach for digesting tough plant matter, cloven hooves, and small, forked horns. Their horns resemble those of the bovids, in that they have a true horny sheath, but, uniquely, they are shed outside the breeding season, and subsequently regrown. Their lateral toes are even further diminished than in bovids, with the digits themselves being entirely lost, and only the cannon bones remaining. Antilocaprids have the same dental formula as most other ruminants: .

The antilocaprids are ruminants of the clade Pecora. Other extant pecorans are the families Giraffidae (giraffes), Cervidae (deer), Moschidae (musk deer), and Bovidae (cattle, goats and sheep, wildebeests and allies, and antelopes). The exact interrelationships among the pecorans have been debated, mainly focusing on the placement of Giraffidae, but a large scale ruminant genome sequencing study in 2019 suggested that Antilocapridae are the sister taxon to Giraffidae, as shown in the cladogram below.

The ancestors of pronghorn diverged from the giraffids in the Early Miocene.