Бенaдрил: Әртүрлі антигистаминдық препараттар мен олардың қолданылуы

Brand of various antihistamine medications

Benadryl is a brand of various antihistamine medications used to stop allergies, whose content varies in different countries, but which includes some combination of diphenhydramine, acrivastine, and/or cetirizine. It is sold by Kenvue and is used to relieve allergy symptoms such as sneezing, itching, runny nose, rash, and hives. or cetirizine. Benadryl is also sold as a cough medicine in Australia, India and New Zealand containing diphenhydramine, as well as the antitussive dextromethorphan or the expectorant guaifenesin.

There are many different forms of Benadryl found in different countries. In the United States and Canada, there are several versions of Benadryl for allergies, some to be taken orally and some as a topical analgesic. In Australia, New Zealand and India, Benadryl is known as a cough liquid.

Benadryl Allergy is the name of a Benadryl product found in the United States and Canada. It is an antihistamine drug used to relieve allergies. Its active ingredient is diphenhydramine, a first generation antihistamine. It is known to be sedative, making drowsiness a common side effect. It is an oral drug to be taken by mouth, to relieve symptoms of allergy, hay fever and the common cold. It can also be used to relieve allergies such as itching, sneezing, runny nose, rash and hives. Benadryl Allergy is widely used as a sleep aid among adults. While it is not marketed as an over the counter (OTC) sleeping aid, most versions of Benadryl contain diphenhydramine, a drug with sedative properties. Diphenhydramine (Benadryl) has also been used by parents to help improve their infant's sleep habits. However, this has been met by criticism on whether it is appropriate to do so.

In the United Kingdom, Benadryl can be found as Benadryl Allergy Relief. The main ingredient in this medication is acrivastine. Acrivastine is a non drowsy antihistamine used to relieve allergies. It can treat hay fever, hives, insect bites and stings, conjunctivitis and eczema. Benadryl Allergy Relief contains 8 mg of acrivastine in each capsule. It is to be taken orally. Benadryl Allergy Relief Plus Decongestant can also be found in the United Kingdom. It is used to relieve sinus, stuffy and runny nose, itchy eyes and sneezing. This version contains acrivastine and pseudoephedrine as its active ingredients. Pseudoephedrine is a decongestant used to relieve a nasal congestion. Benadryl Dry, Tickly Cough Liquid is a cough medicine found in Australia. It is used to temporarily relieve irritating coughs. Pholcodine is the main ingredient found in this cough liquid. This medication is to be taken orally and may cause drowsiness. In India, Benadryl can also be found in the form of a cough liquid and also cough lozenges. Benadryl Cough Syrup contains diphenhydramine, ammonium chloride and citrate as its main ingredients. It is used to relieve cough and cold, and also soothes the throat.

A common side effect of taking Benadryl containing diphenhydramine is drowsiness. Other common side effects can include dry mouth and throat. Symptoms such as confusion and blurred vision can also occur. Other side effects of taking Benadryl include headache and dizziness. Studies propose that long term use of anticholinergic drugs is associated with an increased risk for dementia among older people.

Benadryl containing diphenhydramine can interact with alcohol as both are central nervous system (CNS) depressants. Side effects such as drowsiness and dizziness may be enhanced when taking alcohol with diphenhydramine. Mixing diphenhydramine with alcohol can also increase the chances of losing consciousness due to sedation. This combination can also lead to impaired motor skills and decreased alertness. Driving, operating machinery or any other activities that require full concentration and consciousness are not recommended as these effects persist. Benadryl may interact with other medications such as anti depressants, sleeping pills, muscle relaxants and other antihistamines. It is important to check with a professional before taking Benadryl with any other medications, vitamins and herbal products. In 1946, Benadryl was approved by the Food and Drug Administration (FDA) for prescription use. In 1982 it was approved as an over the counter medication. Before 2007, Benadryl was marketed by Pfizer Consumer Healthcare (originally Warner–Lambert).

On 15 January 2010, McNeil Consumer Healthcare, a subsidiary of Johnson & Johnson, recalled five lots of Benadryl due to the presence of an unusual odor linked to the chemical 2,4,6 tribromoanisole. In April 2010, over four million packs of Benadryl Children Allergy tablets were recalled after it was revealed that they might contain a higher concentration of active ingredients than specified on the label, as well as inactive ingredients that had not met internal testing requirements.

In 2010, after the U. S. Food and Drug Administration (FDA) reported over one hundred cases of mistaken ingestion by mouth, the packaging of Benadryl Itch Stopping Gel was redesigned to include a new warning ("for skin use only"), and a sticker was added as an additional precaution.

Diphenhydramine has a common side effect of drowsiness or sleepiness. The usage of antihistamines as a sleep aid could cause sleepiness during the day, grogginess and falls. That August, an Oklahoma teen reportedly died from a Benadryl overdose. After a later deleted Facebook post by the teen's family member claimed that the death was the result of a "Benadryl challenge," news outlets reported on the dangers of the supposed social media trend. This prompted the FDA to release a statement on the dangers of high doses of diphenhydramine.

Benadryl is available as an over the counter (OTC) drug in most countries. Benadryl can be found in several countries including the United States, Canada, United Kingdom, Australia, New Zealand, India, Indonesia and the Philippines. Benadryl comes in oral tablets and oral liquid to be taken by mouth. Some types of Benadryl such as Benadryl Itch Stopping Cream and gels are meant to be applied to the skin, not to be ingested.